If you ever find yourself having to fight a giant, go for his knees. Knees are the weak spots for giants - for everyone, really, but especially for giants.
Fun fact! Here's Andre with noted Washington QB Joe Theisman - who knows about the weakness of knees - and this meeting happened in part because the Washington Football Concern was curious if Andre the giant could play football. He could not - KNEES - but it's an intriguing idea. Imagine that posse as nosetackle!
Also, some hockey team needs to get a sumo goalie.